node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SER61288.1 | SES38482.1 | SAMN05216199_0677 | SAMN05216199_3179 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.479 |
SER61288.1 | SES45450.1 | SAMN05216199_0677 | SAMN05216199_3796 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Mycoredoxin. | 0.956 |
SER61288.1 | ribB | SAMN05216199_0677 | SAMN05216199_3369 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.796 |
SER62608.1 | SES45450.1 | SAMN05216199_0712 | SAMN05216199_3796 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Mycoredoxin. | 0.648 |
SER62608.1 | msrA | SAMN05216199_0712 | SAMN05216199_4100 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.511 |
SER96266.1 | SES38482.1 | SAMN05216199_1602 | SAMN05216199_3179 | GAF domain-containing protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.744 |
SER96266.1 | SES45450.1 | SAMN05216199_1602 | SAMN05216199_3796 | GAF domain-containing protein. | Mycoredoxin. | 0.567 |
SER96266.1 | SES45485.1 | SAMN05216199_1602 | SAMN05216199_3803 | GAF domain-containing protein. | Adenylate cyclase. | 0.803 |
SER96266.1 | SES48889.1 | SAMN05216199_1602 | SAMN05216199_0239 | GAF domain-containing protein. | PAS domain S-box-containing protein. | 0.839 |
SER96266.1 | ribB | SAMN05216199_1602 | SAMN05216199_3369 | GAF domain-containing protein. | GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.723 |
SES26779.1 | SES38482.1 | SAMN05216199_2659 | SAMN05216199_3179 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.479 |
SES26779.1 | SES45450.1 | SAMN05216199_2659 | SAMN05216199_3796 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Mycoredoxin. | 0.956 |
SES26779.1 | ribB | SAMN05216199_2659 | SAMN05216199_3369 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.796 |
SES38482.1 | SER61288.1 | SAMN05216199_3179 | SAMN05216199_0677 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.479 |
SES38482.1 | SER96266.1 | SAMN05216199_3179 | SAMN05216199_1602 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | GAF domain-containing protein. | 0.744 |
SES38482.1 | SES26779.1 | SAMN05216199_3179 | SAMN05216199_2659 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.479 |
SES38482.1 | SES45450.1 | SAMN05216199_3179 | SAMN05216199_3796 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Mycoredoxin. | 0.778 |
SES38482.1 | SES45485.1 | SAMN05216199_3179 | SAMN05216199_3803 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenylate cyclase. | 0.838 |
SES38482.1 | SES48889.1 | SAMN05216199_3179 | SAMN05216199_0239 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PAS domain S-box-containing protein. | 0.760 |
SES38482.1 | msrA | SAMN05216199_3179 | SAMN05216199_4100 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide-methionine (S)-S-oxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.577 |