Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
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[Homology]
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waaA3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (425 aa)    
Predicted Functional Partners:
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
 0.998
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.969
htrB_1
Lipid A biosynthesis palmitoleoyl acyltransferase; Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (palmitoleoyl)-lipid IV(A); Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.
 
  
 0.964
htrB_2
Lipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
 
  
 0.963
rfaQ
Catalyzes the transfer of heptose(III) to heptose(II) in the lipopolysaccharide inner core; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.963
rfaF
ADP-heptose--LPS heptosyltransferase; Catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.957
rfaC
Lipopolysaccharide heptosyltransferase 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.947
arnT_2
4-amino-4-deoxy-L-arabinose lipid A transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.924
rfaJ_1
Lipopolysaccharide 1,2-glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.924
arnT_1
4-amino-4-deoxy-L-arabinose lipid A transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.
  
  
 0.922
Your Current Organism:
Providencia stuartii
NCBI taxonomy Id: 588
Other names: ATCC 29914, CCUG 14805, CDC 2896-68, CIP 104687, DSM 4539, LMG 3260, LMG:3260, NCTC 11800, P. stuartii, Proteus stuartii
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