STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpap_0423PFAM: AAA ATPase central domain protein; KEGG: tit:Thit_1351 hypothetical protein. (158 aa)    
Predicted Functional Partners:
Cpap_2082
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.996
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.990
Cpap_0424
KEGG: tit:Thit_1350 hypothetical protein.
 
 
 0.975
Cpap_2937
KEGG: cce:Ccel_1954 DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta.
    
 0.968
Cpap_3656
DNA polymerase III, alpha subunit; SMART: phosphoesterase PHP domain protein; TIGRFAM: DNA polymerase III, alpha subunit; KEGG: cce:Ccel_1459 DNA polymerase III DnaE; PFAM: DNA polymerase III alpha subunit; nucleic acid binding OB-fold tRNA/helicase-type; PHP domain protein.
    
 0.968
Cpap_2034
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: cce:Ccel_0365 ATP dependent DNA ligase.
  
 0.966
Cpap_0426
SNF2-related protein; KEGG: tpd:Teth39_0928 helicase domain-containing protein; PFAM: SNF2-related protein; helicase domain protein; SMART: helicase domain protein; DEAD-like helicase.
 
 0.958
Cpap_1644
SMART: helicase c2; DEAD-like helicase; KEGG: cce:Ccel_0660 DEAD_2 domain protein.
  
 0.949
Cpap_0425
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: tit:Thit_1349 DNA methylase N-4/N-6 domain protein.
 
     0.946
Cpap_0428
KEGG: tit:Thit_1346 hypothetical protein.
 
     0.946
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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