STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpap_0651sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. (299 aa)    
Predicted Functional Partners:
Cpap_0309
SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein.
  
  
 0.961
Cpap_0650
RNA polymerase, sigma 28 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.926
Cpap_0649
RNA polymerase, sigma 28 subunit, SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.922
Cpap_1964
KEGG: cce:Ccel_0292 stage II sporulation protein R; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R.
 
   
 0.907
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.903
Cpap_0648
KEGG: cce:Ccel_2060 sporulation protein, YlmC/YmxH family; TIGRFAM: sporulation protein, YlmC/YmxH family; PFAM: PRC-barrel domain protein.
 
     0.861
Cpap_2952
KEGG: cce:Ccel_1944 stage II sporulation protein P; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein.
  
   
 0.847
Cpap_2985
KEGG: cce:Ccel_1916 stage III sporulation protein AA; TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase.
  
  
 0.839
Cpap_2992
KEGG: cce:Ccel_1909 hypothetical protein.
  
  
 0.831
Cpap_2529
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cbt:CLH_0496 sporulation transcriptional regulator spoiiid.
  
  
 0.827
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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