node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cpap_0667 | Cpap_1073 | Cpap_0667 | Cpap_1073 | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. | 0.768 |
Cpap_0667 | Cpap_1917 | Cpap_0667 | Cpap_1917 | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | KEGG: cce:Ccel_0262 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Glycosyl transferase, family 4, conserved region; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.708 |
Cpap_0667 | Cpap_2546 | Cpap_0667 | Cpap_2546 | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | Transferase hexapeptide repeat containing protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.769 |
Cpap_0667 | mraY | Cpap_0667 | Cpap_1076 | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.826 |
Cpap_0667 | murB | Cpap_0667 | Cpap_4152 | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.960 |
Cpap_0667 | murC | Cpap_0667 | Cpap_2543 | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.852 |
Cpap_0667 | murD | Cpap_0667 | Cpap_3174 | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.831 |
Cpap_0667 | murE | Cpap_0667 | Cpap_1074 | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.803 |
Cpap_0667 | murF | Cpap_0667 | Cpap_1075 | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.803 |
Cpap_0667 | murG | Cpap_0667 | Cpap_1078 | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.800 |
Cpap_1073 | Cpap_0667 | Cpap_1073 | Cpap_0667 | KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | 0.768 |
Cpap_1073 | Cpap_2546 | Cpap_1073 | Cpap_2546 | KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. | Transferase hexapeptide repeat containing protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.491 |
Cpap_1073 | mraY | Cpap_1073 | Cpap_1076 | KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.944 |
Cpap_1073 | murB | Cpap_1073 | Cpap_4152 | KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.747 |
Cpap_1073 | murC | Cpap_1073 | Cpap_2543 | KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.906 |
Cpap_1073 | murD | Cpap_1073 | Cpap_3174 | KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.897 |
Cpap_1073 | murE | Cpap_1073 | Cpap_1074 | KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.938 |
Cpap_1073 | murF | Cpap_1073 | Cpap_1075 | KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.968 |
Cpap_1073 | murG | Cpap_1073 | Cpap_1078 | KEGG: cce:Ccel_0478 penicillin-binding protein transpeptidase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; SMART: PASTA domain containing protein. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.839 |
Cpap_1917 | Cpap_0667 | Cpap_1917 | Cpap_0667 | KEGG: cce:Ccel_0262 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Glycosyl transferase, family 4, conserved region; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | KEGG: cth:Cthe_0973 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase). | 0.708 |