STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpap_0919KEGG: cbe:Cbei_2011 isopropylmalate/homocitrate/citramalate synthase-like protein. (318 aa)    
Predicted Functional Partners:
Cpap_0920
PFAM: pyruvate carboxyltransferase; KEGG: cbe:Cbei_2012 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 0.979
Cpap_2096
KEGG: cce:Ccel_0016 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 
 0.907
Cpap_3931
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; KEGG: cce:Ccel_1164 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain.
  
 
 0.907
Cpap_1389
TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; KEGG: cce:Ccel_3433 putative alpha-isopropylmalate/homocitrate synthase family transferase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
  
 0.868
Cpap_0917
TIGRFAM: nitrogenase cofactor biosynthesis protein NifB; PFAM: oxidoreductase/nitrogenase component 1; Radical SAM domain protein; Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: cbe:Cbei_2005 nitrogenase cofactor biosynthesis protein NifB; SMART: Elongator protein 3/MiaB/NifB.
 
  
 0.854
Cpap_0916
KEGG: cbe:Cbei_2004 nitrogenase MoFe cofactor biosynthesis protein NifE; TIGRFAM: nitrogenase MoFe cofactor biosynthesis protein NifE; PFAM: oxidoreductase/nitrogenase component 1; Belongs to the NifD/NifK/NifE/NifN family.
 
  
 0.840
Cpap_4106
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; KR domain protein; Beta-ketoacyl synthase; phosphopantetheine-binding; KEGG: cce:Ccel_2331 amino acid adenylation domain protein; SMART: Polyketide synthase/Fatty acid synthase, KR.
  
 
 0.834
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.819
Cpap_3698
KEGG: cce:Ccel_0932 carbamoyl-phosphate synthase L chain ATP-binding; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; biotin carboxylase domain protein; Carbamoyl-phosphate synthetase large chain domain protein; SMART: biotin carboxylase domain protein.
  
 
 0.786
Cpap_3700
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.786
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.