STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpap_0920PFAM: pyruvate carboxyltransferase; KEGG: cbe:Cbei_2012 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (274 aa)    
Predicted Functional Partners:
Cpap_0919
KEGG: cbe:Cbei_2011 isopropylmalate/homocitrate/citramalate synthase-like protein.
  
 0.979
Cpap_2096
KEGG: cce:Ccel_0016 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 
 0.907
Cpap_3931
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; KEGG: cce:Ccel_1164 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain.
  
 
 0.907
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.864
Cpap_4106
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; KR domain protein; Beta-ketoacyl synthase; phosphopantetheine-binding; KEGG: cce:Ccel_2331 amino acid adenylation domain protein; SMART: Polyketide synthase/Fatty acid synthase, KR.
  
 
 0.834
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
 
 
 0.798
Cpap_0917
TIGRFAM: nitrogenase cofactor biosynthesis protein NifB; PFAM: oxidoreductase/nitrogenase component 1; Radical SAM domain protein; Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: cbe:Cbei_2005 nitrogenase cofactor biosynthesis protein NifB; SMART: Elongator protein 3/MiaB/NifB.
 
  
 0.794
Cpap_0921
KEGG: ckr:CKR_2732 hypothetical protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1.
  
  
 0.781
Cpap_3360
KEGG: cce:Ccel_1264 dihydroxy-acid and 6-phosphogluconate dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.778
ilvD
TIGRFAM: dihydroxy-acid dehydratase; KEGG: cce:Ccel_0302 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.772
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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