STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpap_1284KEGG: cce:Ccel_3312 transcriptional regulator, AbrB family; TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain-containing protein. (80 aa)    
Predicted Functional Partners:
Cpap_3007
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.663
Cpap_0710
KEGG: cth:Cthe_1021 stage IV sporulation protein A; manually curated; PFAM: Sporulation stage IV protein A.
  
     0.658
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
     0.599
Cpap_1283
KEGG: cth:Cthe_2466 hypothetical protein.
       0.566
Cpap_0109
KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A.
  
     0.549
Cpap_2529
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cbt:CLH_0496 sporulation transcriptional regulator spoiiid.
  
   
 0.515
Cpap_4161
KEGG: cce:Ccel_2282 stage V sporulation protein AC; TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein.
  
     0.506
Cpap_1285
Hypothetical protein.
       0.478
Cpap_1286
Helix-turn-helix domain protein; KEGG: apr:Apre_1191 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
       0.461
Cpap_4162
KEGG: cce:Ccel_2281 stage V sporulation protein AD; TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein.
  
     0.459
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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