STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpap_1565KEGG: cce:Ccel_0585 hypothetical protein. (262 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.994
Cpap_1088
KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
  
 0.989
Cpap_0003
6-deoxyerythronolide-B synthase; Manually curated; KEGG: bbe:BBR47_39870 putative mixed polyketide synthase/non-ribosomal peptide synthetase; PFAM: Beta-ketoacyl synthase; phosphopantetheine-binding.
  
 
 0.923
Cpap_3704
PFAM: AMP-dependent synthetase and ligase; condensation domain protein; KEGG: cce:Ccel_0864 amino acid adenylation domain protein.
  
 
 0.923
Cpap_3716
KEGG: cce:Ccel_0862 beta-ketoacyl synthase; PFAM: KR domain protein; Beta-ketoacyl synthase; phosphopantetheine-binding.
  
 
 0.923
Cpap_3631
SMART: AAA ATPase; KEGG: cce:Ccel_1435 AAA ATPase.
  
 0.904
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.898
Cpap_3912
KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA-like domain-containing protein; DsrE family protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; Belongs to the sulfur carrier protein TusA family.
  
 
 0.891
Cpap_4106
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; KR domain protein; Beta-ketoacyl synthase; phosphopantetheine-binding; KEGG: cce:Ccel_2331 amino acid adenylation domain protein; SMART: Polyketide synthase/Fatty acid synthase, KR.
   
 
 0.874
Cpap_3058
PFAM: Rhomboid family protein; KEGG: cce:Ccel_1860 rhomboid family protein.
   
 0.869
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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