STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (250 aa)    
Predicted Functional Partners:
Cpap_1630
Adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; KEGG: cce:Ccel_0644 cobalbumin biosynthesis protein; SMART: AAA ATPase.
 
 
 0.995
Cpap_3371
KEGG: cce:Ccel_1275 precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.995
cobT
Nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
 
 0.990
Cpap_3439
PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: cce:Ccel_1333 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP.
 
 
 0.968
Cpap_1598
KEGG: cce:Ccel_0619 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SMART: Phosphoglycerate mutase.
 
 
 0.959
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.951
Cpap_3368
TIGRFAM: precorrin-4 C11-methyltransferase; KEGG: cce:Ccel_1272 precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
 
 0.947
Cpap_3372
KEGG: cce:Ccel_1276 precorrin-6x reductase; TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK.
 
  
 0.935
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.913
Cpap_3381
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cce:Ccel_1285 precorrin-8X methylmutase CbiC/CobH.
 
  
 0.889
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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