STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpap_2035TIGRFAM: DNA polymerase LigD, polymerase domain protein; KEGG: cce:Ccel_0366 DNA polymerase LigD, polymerase domain protein. (303 aa)    
Predicted Functional Partners:
Cpap_2034
PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein; KEGG: cce:Ccel_0365 ATP dependent DNA ligase.
  
 0.999
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.984
Cpap_2032
TIGRFAM: regulatory protein, FmdB family; PFAM: Putative regulatory protein FmdB; KEGG: cce:Ccel_0363 regulatory protein, FmdB family; SMART: Putative regulatory protein FmdB.
       0.540
Cpap_2036
KEGG: cce:Ccel_0367 UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
       0.505
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
     
 0.496
Cpap_2037
PFAM: Nucleotidyl transferase; KEGG: cce:Ccel_0368 hypothetical protein.
       0.447
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.