STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpap_2328PFAM: protein of unknown function DUF815; KEGG: cce:Ccel_3420 protein of unknown function DUF815. (427 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
   0.534
Cpap_2329
KEGG: cce:Ccel_3419 hypothetical protein.
       0.533
Cpap_2327
KEGG: cce:Ccel_3421 peptidase M14 carboxypeptidase A; PFAM: peptidase M14 carboxypeptidase A; SMART: peptidase M14 carboxypeptidase A.
       0.494
Cpap_2330
KEGG: cce:Ccel_3418 hypothetical protein.
       0.494
Cpap_2331
KEGG: cce:Ccel_3417 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
       0.436
Cpap_2332
KEGG: cce:Ccel_3416 hypothetical protein.
       0.421
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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