| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cpap_0109 | Cpap_0309 | Cpap_0109 | Cpap_0309 | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | 0.789 |
| Cpap_0109 | Cpap_0710 | Cpap_0109 | Cpap_0710 | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | KEGG: cth:Cthe_1021 stage IV sporulation protein A; manually curated; PFAM: Sporulation stage IV protein A. | 0.976 |
| Cpap_0109 | Cpap_1964 | Cpap_0109 | Cpap_1964 | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | KEGG: cce:Ccel_0292 stage II sporulation protein R; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R. | 0.847 |
| Cpap_0109 | Cpap_2529 | Cpap_0109 | Cpap_2529 | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cbt:CLH_0496 sporulation transcriptional regulator spoiiid. | 0.875 |
| Cpap_0109 | Cpap_2551 | Cpap_0109 | Cpap_2551 | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | Stage V sporulation protein T; KEGG: cce:Ccel_3088 transcriptional regulator, AbrB family; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain-containing protein. | 0.779 |
| Cpap_0109 | Cpap_2952 | Cpap_0109 | Cpap_2952 | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | KEGG: cce:Ccel_1944 stage II sporulation protein P; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein. | 0.848 |
| Cpap_0109 | Cpap_2985 | Cpap_0109 | Cpap_2985 | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | KEGG: cce:Ccel_1916 stage III sporulation protein AA; TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase. | 0.854 |
| Cpap_0109 | Cpap_2989 | Cpap_0109 | Cpap_2989 | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | KEGG: cce:Ccel_1912 stage III sporulation protein AE; TIGRFAM: stage III sporulation protein AE; PFAM: Sporulation stage III protein AE. | 0.809 |
| Cpap_0109 | Cpap_2991 | Cpap_0109 | Cpap_2991 | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | KEGG: cce:Ccel_1910 stage III sporulation protein AG. | 0.822 |
| Cpap_0109 | spoIIAB | Cpap_0109 | Cpap_4158 | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.817 |
| Cpap_0309 | Cpap_0109 | Cpap_0309 | Cpap_0109 | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | KEGG: cth:Cthe_1021 stage IV sporulation protein A; TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. | 0.789 |
| Cpap_0309 | Cpap_0710 | Cpap_0309 | Cpap_0710 | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | KEGG: cth:Cthe_1021 stage IV sporulation protein A; manually curated; PFAM: Sporulation stage IV protein A. | 0.764 |
| Cpap_0309 | Cpap_1964 | Cpap_0309 | Cpap_1964 | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | KEGG: cce:Ccel_0292 stage II sporulation protein R; TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R. | 0.890 |
| Cpap_0309 | Cpap_2529 | Cpap_0309 | Cpap_2529 | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: cbt:CLH_0496 sporulation transcriptional regulator spoiiid. | 0.875 |
| Cpap_0309 | Cpap_2551 | Cpap_0309 | Cpap_2551 | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | Stage V sporulation protein T; KEGG: cce:Ccel_3088 transcriptional regulator, AbrB family; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain-containing protein. | 0.803 |
| Cpap_0309 | Cpap_2952 | Cpap_0309 | Cpap_2952 | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | KEGG: cce:Ccel_1944 stage II sporulation protein P; TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein. | 0.876 |
| Cpap_0309 | Cpap_2985 | Cpap_0309 | Cpap_2985 | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | KEGG: cce:Ccel_1916 stage III sporulation protein AA; TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase. | 0.844 |
| Cpap_0309 | Cpap_2989 | Cpap_0309 | Cpap_2989 | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | KEGG: cce:Ccel_1912 stage III sporulation protein AE; TIGRFAM: stage III sporulation protein AE; PFAM: Sporulation stage III protein AE. | 0.771 |
| Cpap_0309 | Cpap_2991 | Cpap_0309 | Cpap_2991 | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | KEGG: cce:Ccel_1910 stage III sporulation protein AG. | 0.811 |
| Cpap_0309 | spoIIAB | Cpap_0309 | Cpap_4158 | SMART: protein phosphatase 2C domain protein; TIGRFAM: stage II sporulation protein E; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation protein E; Cl- channel voltage-gated family protein. | Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.880 |