| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cpap_0530 | Cpap_0833 | Cpap_0530 | Cpap_0833 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cbe:Cbei_1927 NADH:flavin oxidoreductase/NADH oxidase. | Thioredoxin; KEGG: cce:Ccel_2211 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain-containing protein; Belongs to the thioredoxin family. | 0.650 |
| Cpap_0530 | Cpap_2786 | Cpap_0530 | Cpap_2786 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cbe:Cbei_1927 NADH:flavin oxidoreductase/NADH oxidase. | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | 0.810 |
| Cpap_0530 | Cpap_2787 | Cpap_0530 | Cpap_2787 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cbe:Cbei_1927 NADH:flavin oxidoreductase/NADH oxidase. | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | 0.811 |
| Cpap_0530 | Cpap_2880 | Cpap_0530 | Cpap_2880 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cbe:Cbei_1927 NADH:flavin oxidoreductase/NADH oxidase. | PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: sat:SYN_02446 glycerol-3-phosphate dehydrogenase. | 0.495 |
| Cpap_0530 | Cpap_2881 | Cpap_0530 | Cpap_2881 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cbe:Cbei_1927 NADH:flavin oxidoreductase/NADH oxidase. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_02447 pyridine nucleotide-disulphide oxidoreductase family protein. | 0.827 |
| Cpap_0530 | Cpap_3758 | Cpap_0530 | Cpap_3758 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cbe:Cbei_1927 NADH:flavin oxidoreductase/NADH oxidase. | TIGRFAM: redox-active disulfide protein 2; KEGG: cce:Ccel_1067 redox-active disulfide protein 2. | 0.986 |
| Cpap_0530 | Cpap_3912 | Cpap_0530 | Cpap_3912 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cbe:Cbei_1927 NADH:flavin oxidoreductase/NADH oxidase. | KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA-like domain-containing protein; DsrE family protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; Belongs to the sulfur carrier protein TusA family. | 0.960 |
| Cpap_0530 | glyA | Cpap_0530 | Cpap_3226 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cbe:Cbei_1927 NADH:flavin oxidoreductase/NADH oxidase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.596 |
| Cpap_0833 | Cpap_0530 | Cpap_0833 | Cpap_0530 | Thioredoxin; KEGG: cce:Ccel_2211 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain-containing protein; Belongs to the thioredoxin family. | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cbe:Cbei_1927 NADH:flavin oxidoreductase/NADH oxidase. | 0.650 |
| Cpap_0833 | Cpap_2786 | Cpap_0833 | Cpap_2786 | Thioredoxin; KEGG: cce:Ccel_2211 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain-containing protein; Belongs to the thioredoxin family. | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | 0.650 |
| Cpap_0833 | Cpap_2787 | Cpap_0833 | Cpap_2787 | Thioredoxin; KEGG: cce:Ccel_2211 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain-containing protein; Belongs to the thioredoxin family. | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | 0.650 |
| Cpap_0833 | Cpap_2881 | Cpap_0833 | Cpap_2881 | Thioredoxin; KEGG: cce:Ccel_2211 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain-containing protein; Belongs to the thioredoxin family. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_02447 pyridine nucleotide-disulphide oxidoreductase family protein. | 0.910 |
| Cpap_0833 | Cpap_3912 | Cpap_0833 | Cpap_3912 | Thioredoxin; KEGG: cce:Ccel_2211 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain-containing protein; Belongs to the thioredoxin family. | KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA-like domain-containing protein; DsrE family protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; Belongs to the sulfur carrier protein TusA family. | 0.722 |
| Cpap_2786 | Cpap_0530 | Cpap_2786 | Cpap_0530 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cbe:Cbei_1927 NADH:flavin oxidoreductase/NADH oxidase. | 0.810 |
| Cpap_2786 | Cpap_0833 | Cpap_2786 | Cpap_0833 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | Thioredoxin; KEGG: cce:Ccel_2211 thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin domain-containing protein; Belongs to the thioredoxin family. | 0.650 |
| Cpap_2786 | Cpap_2787 | Cpap_2786 | Cpap_2787 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | 0.910 |
| Cpap_2786 | Cpap_2881 | Cpap_2786 | Cpap_2881 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sat:SYN_02447 pyridine nucleotide-disulphide oxidoreductase family protein. | 0.797 |
| Cpap_2786 | Cpap_3758 | Cpap_2786 | Cpap_3758 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | TIGRFAM: redox-active disulfide protein 2; KEGG: cce:Ccel_1067 redox-active disulfide protein 2. | 0.986 |
| Cpap_2786 | Cpap_3912 | Cpap_2786 | Cpap_3912 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | KEGG: cce:Ccel_1144 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA-like domain-containing protein; DsrE family protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Rhodanese domain protein; SMART: Rhodanese domain protein; Belongs to the sulfur carrier protein TusA family. | 0.960 |
| Cpap_2786 | glyA | Cpap_2786 | Cpap_3226 | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: clj:CLJU_c38590 enoate reductase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.596 |