node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cpap_1088 | Cpap_1999 | Cpap_1088 | Cpap_1999 | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | 0.826 |
Cpap_1088 | Cpap_3662 | Cpap_1088 | Cpap_3662 | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | KEGG: cce:Ccel_1465 heat shock protein DnaJ domain protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | 0.992 |
Cpap_1088 | dnaJ | Cpap_1088 | Cpap_3099 | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.992 |
Cpap_1088 | dnaK | Cpap_1088 | Cpap_3098 | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
Cpap_1088 | groL | Cpap_1088 | Cpap_2061 | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.941 |
Cpap_1088 | groL-2 | Cpap_1088 | Cpap_3978 | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.941 |
Cpap_1088 | groS | Cpap_1088 | Cpap_2060 | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.840 |
Cpap_1088 | groS-2 | Cpap_1088 | Cpap_3977 | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.840 |
Cpap_1088 | grpE | Cpap_1088 | Cpap_3097 | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.919 |
Cpap_1999 | Cpap_1088 | Cpap_1999 | Cpap_1088 | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | 0.826 |
Cpap_1999 | Cpap_3662 | Cpap_1999 | Cpap_3662 | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | KEGG: cce:Ccel_1465 heat shock protein DnaJ domain protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | 0.794 |
Cpap_1999 | dnaJ | Cpap_1999 | Cpap_3099 | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.794 |
Cpap_1999 | dnaK | Cpap_1999 | Cpap_3098 | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.984 |
Cpap_1999 | groL | Cpap_1999 | Cpap_2061 | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.708 |
Cpap_1999 | groL-2 | Cpap_1999 | Cpap_3978 | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.708 |
Cpap_1999 | groS | Cpap_1999 | Cpap_2060 | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.733 |
Cpap_1999 | groS-2 | Cpap_1999 | Cpap_3977 | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.733 |
Cpap_1999 | grpE | Cpap_1999 | Cpap_3097 | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.922 |
Cpap_1999 | hrcA | Cpap_1999 | Cpap_3096 | KEGG: cce:Ccel_0327 ATPase AAA-2 domain protein; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; Belongs to the ClpA/ClpB family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.739 |
Cpap_3662 | Cpap_1088 | Cpap_3662 | Cpap_1088 | KEGG: cce:Ccel_1465 heat shock protein DnaJ domain protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. | KEGG: cce:Ccel_0492 heat shock protein 90; PFAM: Heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. | 0.992 |