STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
 0.999
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 
 0.999
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
 
 0.974
Cpap_3108
PFAM: Domain of unknown function DUF2520; Putative oxidoreductase/dehydrogenase, Rossmann-like domain; KEGG: cce:Ccel_1788 hypothetical protein.
 
  
 0.971
cmk
KEGG: cce:Ccel_1729 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
   
  0.925
Cpap_0220
PFAM: Fumble domain protein; KEGG: cce:Ccel_0705 pantothenate kinase.
     
 0.888
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.864
Cpap_2513
KEGG: cce:Ccel_3188 phosphopantothenoylcysteine decarboxylase; PFAM: flavoprotein.
 
 
 0.827
Cpap_3631
SMART: AAA ATPase; KEGG: cce:Ccel_1435 AAA ATPase.
  
  0.812
Cpap_2514
PFAM: DNA/pantothenate metabolism flavoprotein domain protein; KEGG: cce:Ccel_3187 phosphopantothenate--cysteine ligase.
  
 
 0.756
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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