STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addBATP-dependent nuclease subunit B; ATP-dependent DNA helicase; Belongs to the helicase family. AddB/RexB type 1 subfamily. (1148 aa)    
Predicted Functional Partners:
addA
Recombination helicase AddA; ATP-dependent DNA helicase.
 
 
 0.998
Cpap_0193
PFAM: UvrD/REP helicase; NERD domain protein; KEGG: gka:GK1383 hypothetical protein.
  
 
 0.968
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.706
Cpap_3124
PFAM: Abortive infection protein; KEGG: cce:Ccel_1776 abortive infection protein.
       0.702
Cpap_2136
SMART: AAA ATPase; KEGG: cce:Ccel_0052 SMC domain protein.
 
  
 0.626
Cpap_0775
PFAM: FAD dependent oxidoreductase; Rieske [2Fe-2S] iron-sulphur domain; KEGG: cce:Ccel_2448 FAD dependent oxidoreductase.
  
     0.486
Cpap_2407
KEGG: cce:Ccel_3349 hypothetical protein.
  
     0.481
Cpap_3123
KEGG: cce:Ccel_1777 CoA-binding domain protein; PFAM: CoA-binding domain protein; SMART: CoA-binding domain protein.
       0.433
Cpap_0417
PFAM: protein of unknown function DUF633; KEGG: cce:Ccel_0543 protein of unknown function DUF633.
 
     0.429
Cpap_2938
KEGG: cce:Ccel_1953 single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1.
     
 0.417
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
Server load: medium (78%) [HD]