| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cpap_0740 | Cpap_3374 | Cpap_0740 | Cpap_3374 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: cce:Ccel_2474 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.602 |
| Cpap_0740 | Cpap_3383 | Cpap_0740 | Cpap_3383 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: cce:Ccel_2474 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | PFAM: aminotransferase class I and II; KEGG: cce:Ccel_1287 aminotransferase class I and II. | 0.625 |
| Cpap_0740 | Cpap_3386 | Cpap_0740 | Cpap_3386 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: cce:Ccel_2474 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | PFAM: class II aldolase/adducin family protein; KEGG: cce:Ccel_1290 class II aldolase/adducin family protein. | 0.540 |
| Cpap_0740 | Cpap_3514 | Cpap_0740 | Cpap_3514 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: cce:Ccel_2474 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. | 0.600 |
| Cpap_0740 | mtnA | Cpap_0740 | Cpap_3385 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: cce:Ccel_2474 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.838 |
| Cpap_0740 | mtnK | Cpap_0740 | Cpap_3384 | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: cce:Ccel_2474 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | 5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.807 |
| Cpap_3374 | Cpap_0740 | Cpap_3374 | Cpap_0740 | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: cce:Ccel_2474 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein. | 0.602 |
| Cpap_3374 | Cpap_3381 | Cpap_3374 | Cpap_3381 | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cce:Ccel_1285 precorrin-8X methylmutase CbiC/CobH. | 0.938 |
| Cpap_3374 | Cpap_3383 | Cpap_3374 | Cpap_3383 | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | PFAM: aminotransferase class I and II; KEGG: cce:Ccel_1287 aminotransferase class I and II. | 0.917 |
| Cpap_3374 | Cpap_3386 | Cpap_3374 | Cpap_3386 | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | PFAM: class II aldolase/adducin family protein; KEGG: cce:Ccel_1290 class II aldolase/adducin family protein. | 0.587 |
| Cpap_3374 | Cpap_3387 | Cpap_3374 | Cpap_3387 | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | KEGG: lsg:lse_1013 hypothetical protein. | 0.535 |
| Cpap_3374 | cobD | Cpap_3374 | Cpap_3382 | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.935 |
| Cpap_3374 | cobQ | Cpap_3374 | Cpap_3380 | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.927 |
| Cpap_3374 | mtnA | Cpap_3374 | Cpap_3385 | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.619 |
| Cpap_3374 | mtnK | Cpap_3374 | Cpap_3384 | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 5-methylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. | 0.596 |
| Cpap_3381 | Cpap_3374 | Cpap_3381 | Cpap_3374 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cce:Ccel_1285 precorrin-8X methylmutase CbiC/CobH. | KEGG: cce:Ccel_1278 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. | 0.938 |
| Cpap_3381 | Cpap_3383 | Cpap_3381 | Cpap_3383 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cce:Ccel_1285 precorrin-8X methylmutase CbiC/CobH. | PFAM: aminotransferase class I and II; KEGG: cce:Ccel_1287 aminotransferase class I and II. | 0.971 |
| Cpap_3381 | Cpap_3386 | Cpap_3381 | Cpap_3386 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cce:Ccel_1285 precorrin-8X methylmutase CbiC/CobH. | PFAM: class II aldolase/adducin family protein; KEGG: cce:Ccel_1290 class II aldolase/adducin family protein. | 0.596 |
| Cpap_3381 | Cpap_3387 | Cpap_3381 | Cpap_3387 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cce:Ccel_1285 precorrin-8X methylmutase CbiC/CobH. | KEGG: lsg:lse_1013 hypothetical protein. | 0.553 |
| Cpap_3381 | cobD | Cpap_3381 | Cpap_3382 | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cce:Ccel_1285 precorrin-8X methylmutase CbiC/CobH. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.990 |