STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpap_3403PFAM: pentapeptide repeat protein; KEGG: rpr:RP563 hypothetical protein. (515 aa)    
Predicted Functional Partners:
Cpap_2102
Peptidoglycan-binding lysin domain; KEGG: cce:Ccel_0021 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
   
 
 0.658
Cpap_0870
PFAM: Abortive phage infection; KEGG: dhd:Dhaf_2826 hypothetical protein.
    
 
 0.616
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.616
Cpap_3588
KEGG: cce:Ccel_1398 DNA gyrase subunit B domain protein; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; TOPRIM domain-containing protein; DNA gyrase subunit B domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein.
    
 
 0.616
Cpap_3731
PFAM: S-layer domain-containing protein; Listeria/Bacterioides repeat-containing protein; KEGG: cce:Ccel_2644 cell wall/surface repeat protein.
  
 
 0.607
Cpap_1909
KEGG: cce:Ccel_0254 hypothetical protein.
   
   0.596
Cpap_3586
KEGG: cce:Ccel_1396 hypothetical protein.
   
   0.596
Cpap_3404
KEGG: eum:ECUMN_2310 hypothetical protein.
  
    0.584
Cpap_4182
PFAM: pentapeptide repeat protein; KEGG: cce:Ccel_2262 pentapeptide repeat protein.
 
     0.556
Cpap_2669
KEGG: cce:Ccel_2569 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; Belongs to the pyruvate kinase family.
    
 0.512
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
Server load: medium (68%) [HD]