STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cpap_3478PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; KEGG: cth:Cthe_0645 methionine synthase (B12-dependent). (811 aa)    
Predicted Functional Partners:
Cpap_0740
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: cce:Ccel_2474 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
 
 
0.999
Cpap_2756
TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: ere:EUBREC_2200 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
 
 
 0.998
Cpap_0231
PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: clj:CLJU_c24380 cystathione gamma-synthase.
  
 
 0.969
Cpap_3477
PFAM: Vitamin B12 dependent methionine synthase activation region; KEGG: cth:Cthe_0644 vitamin B12 dependent methionine synthase, activation region.
 
 
 0.967
Cpap_3649
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: cce:Ccel_1452 homoserine dehydrogenase.
  
 
 0.954
Cpap_2439
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: cce:Ccel_3332 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
  
 
 0.952
Cpap_3931
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; KEGG: cce:Ccel_1164 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain.
    
 0.948
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.930
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
 0.929
Cpap_2929
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: cce:Ccel_1962 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein.
  
 
 0.920
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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