Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
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Textmining
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
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Coexpression
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
KEGG: cce:Ccel_1398 DNA gyrase subunit B domain protein; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; TOPRIM domain-containing protein; DNA gyrase subunit B domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein.
0.467
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581 Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1
node2
node1 annotation
node2 annotation
score
Cpap_3587
Cpap_3588
KEGG: cce:Ccel_1397 hypothetical protein.
KEGG: cce:Ccel_1398 DNA gyrase subunit B domain protein; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; TOPRIM domain-containing protein; DNA gyrase subunit B domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein.
0.467
Cpap_3588
Cpap_3587
KEGG: cce:Ccel_1398 DNA gyrase subunit B domain protein; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; TOPRIM domain-containing protein; DNA gyrase subunit B domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein.
KEGG: cce:Ccel_1397 hypothetical protein.
0.467
Network Stats
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Functional enrichments in your networkNote: some enrichments may be expected here (why?) disable highlightexplain columns
Enrichment analysis is still ongoing, please wait ...
Statistical background
For the above enrichment analysis, the following statistical background is assumed: