STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (190 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 0.991
Cpap_2063
PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; KEGG: cce:Ccel_0394 inosine 5-monophosphate dehydrogenase; SMART: CBS domain containing protein.
  
 
 0.941
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.938
deoD
KEGG: cce:Ccel_3381 purine nucleoside phosphorylase; TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1.
    
 0.882
Cpap_2155
TIGRFAM: hypoxanthine phosphoribosyltransferase; KEGG: cce:Ccel_0084 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
   
 0.877
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.877
Cpap_3501
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
 0.855
Cpap_1903
Inorganic diphosphatase; PFAM: DHHA2 domain protein; DRTGG domain protein; CBS domain containing protein; phosphoesterase RecJ domain protein; KEGG: cce:Ccel_0248 putative manganese-dependent inorganic pyrophosphatase; SMART: CBS domain containing protein.
 
 
 0.823
Cpap_1094
TIGRFAM: phosphoribosylformylglycinamidine synthase; KEGG: cce:Ccel_0499 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
  
  
 0.817
Cpap_3785
PFAM: PfkB domain protein; KEGG: cce:Ccel_1080 PfkB domain protein.
   
 0.817
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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