STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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nadENAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (642 aa)    
Predicted Functional Partners:
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.974
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.947
cinA
TIGRFAM: competence/damage-inducible protein CinA; molybdenum cofactor synthesis domain protein; PFAM: CinA domain protein; molybdopterin binding domain; KEGG: cce:Ccel_0674 competence/damage-inducible protein CinA; SMART: molybdopterin binding domain.
    
 0.939
cobB
Silent information regulator protein Sir2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
   
 0.936
Cpap_0327
NAD(+) diphosphatase; KEGG: cce:Ccel_2937 NUDIX hydrolase; PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase.
  
 
 0.916
Cpap_3931
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; KEGG: cce:Ccel_1164 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain.
  
 
  0.916
Cpap_2096
KEGG: cce:Ccel_0016 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain.
  
 
  0.914
Cpap_0281
Hypothetical protein; KEGG: cce:Ccel_0862 beta-ketoacyl synthase.
  
 0.911
Cpap_2812
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; KEGG: clj:CLJU_c30260 putative oxidoreductase.
  
 0.902
Cpap_3651
KEGG: cce:Ccel_1454 hypothetical protein.
  
 0.897
Your Current Organism:
Ruminiclostridium papyrosolvens DSM 2782
NCBI taxonomy Id: 588581
Other names: Clostridium papyrosolvens DSM 2782, R. papyrosolvens DSM 2782
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