| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SFI49800.1 | SFJ20317.1 | SAMN04487991_0089 | SAMN04487991_1663 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | 0.414 |
| SFI49800.1 | glmS | SAMN04487991_0089 | SAMN04487991_0271 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.490 |
| SFI49800.1 | guaA | SAMN04487991_0089 | SAMN04487991_1069 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.723 |
| SFI49800.1 | murD | SAMN04487991_0089 | SAMN04487991_1615 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.536 |
| SFI49800.1 | murE | SAMN04487991_0089 | SAMN04487991_1620 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.460 |
| SFI49800.1 | ribB | SAMN04487991_0089 | SAMN04487991_0095 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
| SFJ20287.1 | SFJ20317.1 | SAMN04487991_1662 | SAMN04487991_1663 | TatD DNase family protein. | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | 0.869 |
| SFJ20287.1 | SFJ20352.1 | SAMN04487991_1662 | SAMN04487991_1664 | TatD DNase family protein. | Hypothetical protein. | 0.700 |
| SFJ20287.1 | SFJ20402.1 | SAMN04487991_1662 | SAMN04487991_1665 | TatD DNase family protein. | Predicted P-loop ATPase, KAP-like. | 0.865 |
| SFJ20317.1 | SFI49800.1 | SAMN04487991_1663 | SAMN04487991_0089 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.414 |
| SFJ20317.1 | SFJ20287.1 | SAMN04487991_1663 | SAMN04487991_1662 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | TatD DNase family protein. | 0.869 |
| SFJ20317.1 | SFJ20352.1 | SAMN04487991_1663 | SAMN04487991_1664 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | Hypothetical protein. | 0.801 |
| SFJ20317.1 | SFJ20402.1 | SAMN04487991_1663 | SAMN04487991_1665 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | Predicted P-loop ATPase, KAP-like. | 0.956 |
| SFJ20317.1 | glmS | SAMN04487991_1663 | SAMN04487991_0271 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.496 |
| SFJ20317.1 | guaA | SAMN04487991_1663 | SAMN04487991_1069 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.416 |
| SFJ20317.1 | murD | SAMN04487991_1663 | SAMN04487991_1615 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.445 |
| SFJ20317.1 | murE | SAMN04487991_1663 | SAMN04487991_1620 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.406 |
| SFJ20317.1 | queF | SAMN04487991_1663 | SAMN04487991_3347 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.826 |
| SFJ20317.1 | ribB | SAMN04487991_1663 | SAMN04487991_0095 | 7-cyano-7-deazaguanine synthase (queuosine biosynthesis). | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.406 |
| SFJ20352.1 | SFJ20287.1 | SAMN04487991_1664 | SAMN04487991_1662 | Hypothetical protein. | TatD DNase family protein. | 0.700 |