STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0BMK4_PARTEUncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (274 aa)    
Predicted Functional Partners:
DRTS_PARTE
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.
  
 
 0.829
A0C3X5_PARTE
2Fe-2S ferredoxin-type domain-containing protein.
  
 0.818
A0E082_PARTE
2Fe-2S ferredoxin-type domain-containing protein.
  
 0.818
A0BFG8_PARTE
Uncharacterized protein.
   
 
 0.801
A0C5R4_PARTE
ULP_PROTEASE domain-containing protein.
   
 
 0.801
A0CBS0_PARTE
ULP_PROTEASE domain-containing protein.
   
 
 0.801
A0CCP3_PARTE
Uncharacterized protein.
   
 
 0.801
A0E355_PARTE
Uncharacterized protein.
   
 
 0.801
A0E395_PARTE
PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 0.792
A0BGY1_PARTE
PKS_AT domain-containing protein.
  
 
 0.712
Your Current Organism:
Paramecium tetraurelia
NCBI taxonomy Id: 5888
Other names: P. tetraurelia, Paramecium aurelia syngen 4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.