STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0CDJ2_PARTEMFS domain-containing protein. (433 aa)    
Predicted Functional Partners:
DRTS_PARTE
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.
    
 0.599
A0CUS0_PARTE
Uncharacterized protein.
  
     0.512
A0D552_PARTE
Glyceraldehyde-3-phosphate dehydrogenase.
   
 0.493
A0DHJ8_PARTE
Glyceraldehyde-3-phosphate dehydrogenase.
   
 0.493
A0CLX1_PARTE
Uncharacterized protein.
  
     0.488
A0D3P5_PARTE
Uncharacterized protein.
  
     0.487
A0D815_PARTE
MFS domain-containing protein.
  
     0.432
A0BQP9_PARTE
Uncharacterized protein.
    
  0.424
A0BF49_PARTE
Thymidine kinase.
     
 0.403
A0C3Z8_PARTE
Thymidine kinase.
     
 0.403
Your Current Organism:
Paramecium tetraurelia
NCBI taxonomy Id: 5888
Other names: P. tetraurelia, Paramecium aurelia syngen 4
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