STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0CDN4_PARTEHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (116 aa)    
Predicted Functional Partners:
A0BED6_PARTE
Histone H2A; Belongs to the histone H2A family.
   
 0.982
A0C2C9_PARTE
Histone H2A; Belongs to the histone H2A family.
   
 0.982
A0CD29_PARTE
Histone H2A; Belongs to the histone H2A family.
   
 0.982
A0DTL9_PARTE
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.980
A0CVR0_PARTE
Hat1_N domain-containing protein.
    
 0.976
A0D956_PARTE
Hat1_N domain-containing protein.
    
 0.976
A0BG67_PARTE
Histone domain-containing protein.
   
 0.962
A0BYI3_PARTE
Histone domain-containing protein.
   
 0.962
A0CA24_PARTE
Histone domain-containing protein.
   
 0.962
A0CXG6_PARTE
Histone domain-containing protein.
   
 0.962
Your Current Organism:
Paramecium tetraurelia
NCBI taxonomy Id: 5888
Other names: P. tetraurelia, Paramecium aurelia syngen 4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.