STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0CKK9_PARTEThymidylate_kin domain-containing protein. (216 aa)    
Predicted Functional Partners:
DRTS_PARTE
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.
  
 
 0.991
A0BF49_PARTE
Thymidine kinase.
  
 
 0.981
A0C3Z8_PARTE
Thymidine kinase.
  
 
 0.981
A0CA73_PARTE
Thymidine kinase.
  
 
 0.981
A0CEQ2_PARTE
Thymidine kinase.
  
 
 0.981
A0EBL9_PARTE
dUTPase domain-containing protein.
  
 
 0.979
A0BRH0_PARTE
CMP/dCMP-type deaminase domain-containing protein.
    
 0.977
A0CJX5_PARTE
CMP/dCMP-type deaminase domain-containing protein.
    
 0.977
A0C9U7_PARTE
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.975
A0DGX0_PARTE
RIBORED_LARGE domain-containing protein.
  
 
 0.975
Your Current Organism:
Paramecium tetraurelia
NCBI taxonomy Id: 5888
Other names: P. tetraurelia, Paramecium aurelia syngen 4
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.