STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0DYA0_PARTEUncharacterized protein; Belongs to the cyclin family. (491 aa)    
Predicted Functional Partners:
A0C2H8_PARTE
Protein kinase domain-containing protein.
   
 
 0.614
A0CNX3_PARTE
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.614
A0E3H1_PARTE
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.614
A0EE13_PARTE
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.614
A0D049_PARTE
Protein kinase domain-containing protein.
      
 0.495
A0CQL4_PARTE
Protein kinase domain-containing protein.
      
 0.436
A0D4S6_PARTE
Protein kinase domain-containing protein.
      
 0.436
A0DT39_PARTE
Protein kinase domain-containing protein.
      
 0.436
A0EBH8_PARTE
Uncharacterized protein.
      
 0.436
DRTS_PARTE
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity); In the N-terminal section; belongs to the dihydrofolate reductase family.
      
 0.428
Your Current Organism:
Paramecium tetraurelia
NCBI taxonomy Id: 5888
Other names: P. tetraurelia, Paramecium aurelia syngen 4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.