STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDS77761.15-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (511 aa)    
Predicted Functional Partners:
SDS77665.1
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
 
 
 0.947
SDS77799.1
3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
 
 0.945
SDS77716.1
DNA-binding transcriptional regulator, GntR family.
  
  0.892
SDS77604.1
2,4-dihydroxyhept-2-enedioate aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 
  0.841
SDS77538.1
2-oxohept-3-enedioate hydratase.
 
    0.836
SDS28626.1
Glutamate synthase (NADH) large subunit.
  
 
 0.819
SDT36914.1
phenylacetate-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
   
  0.672
SDS81843.1
Phosphate acetyltransferase.
  
 
 0.660
SDS77284.1
Acetolactate synthase large subunit; Belongs to the TPP enzyme family.
 
 
  0.633
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
  0.592
Your Current Organism:
Agromyces flavus
NCBI taxonomy Id: 589382
Other names: A. flavus, Agromyces flavus Chen et al. 2011, Agromyces sp. CPCC 202695, CCM 7623, CPCC 202695, KCTC 19578
Server load: low (30%) [HD]