node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADH85056.1 | hisB | DaAHT2_0350 | DaAHT2_0351 | PFAM: PP-loop domain protein; KEGG: dps:DP1330 hypothetical protein; Belongs to the TtcA family. | KEGG: ppd:Ppro_3040 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. | 0.785 |
ADH85056.1 | hisH | DaAHT2_0350 | DaAHT2_2087 | PFAM: PP-loop domain protein; KEGG: dps:DP1330 hypothetical protein; Belongs to the TtcA family. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family. | 0.701 |
ADH86286.1 | ADH86454.1 | DaAHT2_1591 | DaAHT2_1763 | KEGG: gur:Gura_0043 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. | PFAM: UbiA prenyltransferase; KEGG: mxa:MXAN_6629 hypothetical protein. | 0.634 |
ADH86286.1 | ADH86958.1 | DaAHT2_1591 | DaAHT2_2293 | KEGG: gur:Gura_0043 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. | KEGG: dps:DP0005 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; Belongs to the HisA/HisF family. | 0.816 |
ADH86286.1 | hisB | DaAHT2_1591 | DaAHT2_0351 | KEGG: gur:Gura_0043 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. | KEGG: ppd:Ppro_3040 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. | 0.982 |
ADH86286.1 | hisD | DaAHT2_1591 | DaAHT2_1943 | KEGG: gur:Gura_0043 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.975 |
ADH86286.1 | hisG | DaAHT2_1591 | DaAHT2_1355 | KEGG: gur:Gura_0043 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.841 |
ADH86286.1 | hisH | DaAHT2_1591 | DaAHT2_2087 | KEGG: gur:Gura_0043 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family. | 0.997 |
ADH86286.1 | hisI | DaAHT2_1591 | DaAHT2_1356 | KEGG: gur:Gura_0043 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.877 |
ADH86454.1 | ADH86286.1 | DaAHT2_1763 | DaAHT2_1591 | PFAM: UbiA prenyltransferase; KEGG: mxa:MXAN_6629 hypothetical protein. | KEGG: gur:Gura_0043 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. | 0.634 |
ADH86454.1 | ADH86958.1 | DaAHT2_1763 | DaAHT2_2293 | PFAM: UbiA prenyltransferase; KEGG: mxa:MXAN_6629 hypothetical protein. | KEGG: dps:DP0005 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; Belongs to the HisA/HisF family. | 0.765 |
ADH86454.1 | hisB | DaAHT2_1763 | DaAHT2_0351 | PFAM: UbiA prenyltransferase; KEGG: mxa:MXAN_6629 hypothetical protein. | KEGG: ppd:Ppro_3040 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. | 0.803 |
ADH86454.1 | hisC | DaAHT2_1763 | DaAHT2_2672 | PFAM: UbiA prenyltransferase; KEGG: mxa:MXAN_6629 hypothetical protein. | KEGG: dps:DP0642 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.634 |
ADH86454.1 | hisD | DaAHT2_1763 | DaAHT2_1943 | PFAM: UbiA prenyltransferase; KEGG: mxa:MXAN_6629 hypothetical protein. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.764 |
ADH86454.1 | hisG | DaAHT2_1763 | DaAHT2_1355 | PFAM: UbiA prenyltransferase; KEGG: mxa:MXAN_6629 hypothetical protein. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.664 |
ADH86454.1 | hisH | DaAHT2_1763 | DaAHT2_2087 | PFAM: UbiA prenyltransferase; KEGG: mxa:MXAN_6629 hypothetical protein. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF; Belongs to the HisA/HisF family. | 0.996 |
ADH86454.1 | hisI | DaAHT2_1763 | DaAHT2_1356 | PFAM: UbiA prenyltransferase; KEGG: mxa:MXAN_6629 hypothetical protein. | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.798 |
ADH86958.1 | ADH86286.1 | DaAHT2_2293 | DaAHT2_1591 | KEGG: dps:DP0005 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; Belongs to the HisA/HisF family. | KEGG: gur:Gura_0043 putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II. | 0.816 |
ADH86958.1 | ADH86454.1 | DaAHT2_2293 | DaAHT2_1763 | KEGG: dps:DP0005 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; Belongs to the HisA/HisF family. | PFAM: UbiA prenyltransferase; KEGG: mxa:MXAN_6629 hypothetical protein. | 0.765 |
ADH86958.1 | hisB | DaAHT2_2293 | DaAHT2_0351 | KEGG: dps:DP0005 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; Belongs to the HisA/HisF family. | KEGG: ppd:Ppro_3040 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase. | 0.954 |