STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH85329.1PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase FKBP-type; KEGG: pca:Pcar_0774 FKBP-type peptidyl-prolyl cis-trans isomerase. (237 aa)    
Predicted Functional Partners:
infA
Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
   
   0.829
ADH85665.1
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
 
 0.807
ADH85781.1
KEGG: app:CAP2UW1_4193 conserved hypothetical protein, predicted protein kinase family.
    
 0.764
zupT
Zinc/iron permease; Mediates zinc uptake. May also transport other divalent cations; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
       0.746
ADH86853.1
PFAM: ATP-binding region ATPase domain protein; KEGG: sfu:Sfum_3853 hypothetical protein.
   
 0.680
htpG
Heat shock protein Hsp90-like protein; Molecular chaperone. Has ATPase activity.
   
 0.680
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
 
  
 0.678
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.672
ADH84870.1
DNA-directed DNA polymerase; KEGG: dma:DMR_28930 UmuC protein; PFAM: UMUC domain protein DNA-repair protein.
    
 
 0.583
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.558
Your Current Organism:
Desulfurivibrio alkaliphilus
NCBI taxonomy Id: 589865
Other names: D. alkaliphilus AHT 2, Desulfurivibrio alkaliphilus AHT 2, Desulfurivibrio alkaliphilus str. AHT 2, Desulfurivibrio alkaliphilus strain AHT 2
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