STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH85421.1KEGG: drt:Dret_1057 C_GCAxxG_C_C family protein; TIGRFAM: C_GCAxxG_C_C family protein; PFAM: C_GCAxxG_C_C family protein. (163 aa)    
Predicted Functional Partners:
ADH86810.1
KEGG: hha:Hhal_0052 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase.
  
 
 0.513
msrA
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.509
ADH85325.1
PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; KEGG: dps:DP2171 P-protein.
     
 0.506
ADH85140.1
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: dps:DP2275 P-protein.
     
 0.494
ADH84849.1
TIGRFAM: selenium metabolism protein YedF; KEGG: ppd:Ppro_1708 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
 
     0.481
nth
Exodeoxyribonuclease III Xth; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
  
 0.472
recD
Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...]
     
 0.464
ADH85417.1
PFAM: Extracellular ligand-binding receptor; KEGG: har:HEAR1728 putative extracellular ligand-binding receptor.
       0.458
ADH85418.1
Integral membrane sensor signal transduction histidine kinase; KEGG: ppd:Ppro_2089 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
       0.458
ADH85420.1
PFAM: Fe-S cluster domain protein; KEGG: dol:Dole_1535 Fe-S cluster domain-containing protein.
       0.458
Your Current Organism:
Desulfurivibrio alkaliphilus
NCBI taxonomy Id: 589865
Other names: D. alkaliphilus AHT 2, Desulfurivibrio alkaliphilus AHT 2, Desulfurivibrio alkaliphilus str. AHT 2, Desulfurivibrio alkaliphilus strain AHT 2
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