Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADH85513.1PFAM: Peptidase M23; KEGG: hch:HCH_06239 membrane protein related to metalloendopeptidase. (473 aa)    
Predicted Functional Partners:
trmL
tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
  
    0.773
ADH85895.1
PFAM: Peptidase M23; KEGG: dps:DP2555 lipoprotein NlpD/LppB.
 
   
 0.677
ADH84957.1
Penicillin-binding protein, 1A family; KEGG: sat:SYN_00304 multimodular transpeptidase-transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase.
  
   
 0.582
uppP
Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
 
    0.513
rlpA
Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
 
 
 0.475
ADH86979.1
TIGRFAM: signal peptidase I; KEGG: sat:SYN_01527 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family.
 
  
 0.472
ADH86382.1
KEGG: dps:DP1676 membrane-bound lytic murein transglycosylase D [precursor]; PFAM: Lytic transglycosylase catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM.
 
   
 0.422
ADH85512.1
KEGG: dol:Dole_0773 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family.
     
 0.405
Your Current Organism:
Desulfurivibrio alkaliphilus
NCBI taxonomy Id: 589865
Other names: D. alkaliphilus AHT 2, Desulfurivibrio alkaliphilus AHT 2, Desulfurivibrio alkaliphilus str. AHT 2, Desulfurivibrio alkaliphilus strain AHT 2
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