Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADH85662.1Signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: dps:DP2722 Ntr two-component system sensor histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein. (576 aa)    
Predicted Functional Partners:
ADH85661.1
Two component, sigma54 specific, transcriptional regulator, Fis family; KEGG: dps:DP2721 Ntr family protein two-component system response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase.
 
  0.989
ADH86871.1
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 0.907
ADH85804.1
KEGG: dal:Dalk_3211 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
 
   0.797
ADH86770.1
KEGG: mgm:Mmc1_3443 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; regulatory protein ArsR.
  
 
 0.783
ADH87063.1
Response regulator receiver protein; KEGG: gem:GM21_0268 two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver; SMART: response regulator receiver.
  
   0.780
ADH86240.1
KEGG: dal:Dalk_2141 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein.
  
 
   0.740
ADH87173.1
KEGG: dsa:Desal_1136 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
  
   0.692
ADH87177.1
KEGG: dba:Dbac_1807 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
  
   0.692
ADH85220.1
KEGG: lch:Lcho_2296 response regulator receiver sensor signal transduction histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver.
  
 
   0.680
ADH86265.1
Two component transcriptional regulator, winged helix family; KEGG: dps:DP1885 PHO two-component system sensor histidine kinase; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver.
 
 
   0.678
Your Current Organism:
Desulfurivibrio alkaliphilus
NCBI taxonomy Id: 589865
Other names: D. alkaliphilus AHT 2, Desulfurivibrio alkaliphilus AHT 2, Desulfurivibrio alkaliphilus str. AHT 2, Desulfurivibrio alkaliphilus strain AHT 2
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.