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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
ADH85809.1PFAM: CoA-binding domain protein; ATP-grasp domain protein; KEGG: dps:DP0658 acetyl-CoA synthetase. (699 aa)    
Predicted Functional Partners:
ADH85810.1
PFAM: acetyl-CoA hydrolase/transferase; GCN5-related N-acetyltransferase; KEGG: dps:DP0659 4-hydroxybutyrate CoA-transferase.
     0.984
ADH85610.1
KEGG: dps:DP2886 pyruvate-flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; Pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding.
  
 0.963
ADH84913.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 0.940
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.924
ADH85511.1
KEGG: dps:DP0660 putative alpha-isopropylmalate/homocitrate synthase family transferase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
  
  0.916
ADH84912.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; KEGG: drt:Dret_0516 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding.
    
 0.910
ADH86744.1
Quinone oxidoreductase, YhdH/YhfP family; KEGG: btl:BALH_0714 alcohol dehydrogenase, zinc-containing; TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein.
     
 0.901
ADH85167.1
Acetyl-CoA carboxylase; KEGG: dps:DP1813 acetyl-coenzyme A carboxylase subunits alpha/beta; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region.
     
  0.900
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
    
  0.900
ADH87142.1
PFAM: pyruvate carboxyltransferase; KEGG: dvm:DvMF_2612 pyruvate carboxyltransferase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
    
  0.900
Your Current Organism:
Desulfurivibrio alkaliphilus
NCBI taxonomy Id: 589865
Other names: D. alkaliphilus AHT 2, Desulfurivibrio alkaliphilus AHT 2, Desulfurivibrio alkaliphilus str. AHT 2, Desulfurivibrio alkaliphilus strain AHT 2
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