Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADH86650.1Radical SAM domain protein; KEGG: dps:DP2744 Mg-protoporphyrin IX monomethyl ester oxidative cyclase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (601 aa)    
Predicted Functional Partners:
ADH85752.1
PFAM: SEC-C motif domain protein; KEGG: dps:DP2826 hypothetical protein.
  
     0.582
ADH85556.1
PFAM: 4-vinyl reductase 4VR; KEGG: dma:DMR_41680 hypothetical protein.
  
  
 0.579
ADH85824.1
Radical SAM domain protein; KEGG: dps:DP1853 methyltransferase; PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.541
ADH85835.1
Radical SAM domain protein; KEGG: ppd:Ppro_2479 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase; PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.505
ADH86648.1
TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; response regulator receiver; PAS fold-4 domain protein; KEGG: dsa:Desal_1230 diguanylate cyclase with PAS/PAC sensor; SMART: GGDEF domain containing protein; response regulator receiver.
       0.501
ddl
D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
       0.501
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
       0.497
ADH86652.1
PFAM: peptidase M16 domain protein; KEGG: mxa:MXAN_1141 M16 family peptidase; Belongs to the peptidase M16 family.
       0.482
ADH86759.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
      0.408
ADH87076.1
KEGG: mpl:Mpal_0643 radical SAM domain protein; PFAM: Radical SAM domain protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB.
  
     0.407
Your Current Organism:
Desulfurivibrio alkaliphilus
NCBI taxonomy Id: 589865
Other names: D. alkaliphilus AHT 2, Desulfurivibrio alkaliphilus AHT 2, Desulfurivibrio alkaliphilus str. AHT 2, Desulfurivibrio alkaliphilus strain AHT 2
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