STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADH86667.1PFAM: protein of unknown function DUF1538; KEGG: chy:CHY_1193 hypothetical protein. (242 aa)    
Predicted Functional Partners:
ADH86668.1
KEGG: chy:CHY_1194 PII family protein.
     0.980
ADH84797.1
KEGG: mgm:Mmc1_0100 nitrogen regulatory protein P-II.
 
     0.786
ADH85339.1
PFAM: nitrogen regulatory protein P-II; KEGG: nth:Nther_0344 nitrogen regulatory protein P-II.
 
     0.784
ADH86666.1
PFAM: protein of unknown function DUF1538; KEGG: chy:CHY_1192 hypothetical protein.
 
    
0.747
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.451
ADH86669.1
PFAM: dihydropteroate synthase DHPS; KEGG: dol:Dole_3182 dihydropteroate synthase DhpS.
       0.449
ADH85140.1
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: dps:DP2275 P-protein.
  
    0.447
ADH86678.1
PFAM: phosphoribosyltransferase; KEGG: gsu:GSU0124 competence protein F, putative.
   
    0.446
Your Current Organism:
Desulfurivibrio alkaliphilus
NCBI taxonomy Id: 589865
Other names: D. alkaliphilus AHT 2, Desulfurivibrio alkaliphilus AHT 2, Desulfurivibrio alkaliphilus str. AHT 2, Desulfurivibrio alkaliphilus strain AHT 2
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