STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ferp_0063PFAM: amino acid-binding ACT domain protein; KEGG: afu:AF0934 hypothetical protein. (165 aa)    
Predicted Functional Partners:
Ferp_0061
PFAM: Peptidase A24B, FlaK domain protein; peptidase A24A prepilin type IV; KEGG: afu:AF0936 hypothetical protein.
 
     0.850
Ferp_0062
PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; KEGG: afu:AF0935 homoserine dehydrogenase.
 
     0.839
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
       0.800
Ferp_0286
PFAM: Protein of unknown function DUF509; KEGG: afu:AF0519 hypothetical protein.
  
     0.685
cofC
2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.678
Ferp_1407
PFAM: Exosortase EpsH-related; KEGG: afu:AF2046 cytochrome oxidase, subunit I, putative.
  
     0.662
Ferp_1319
PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: afu:AF0780 replication factor A.
  
     0.624
Ferp_0355
Putative transcriptional regulator, AsnC family; PFAM: regulatory protein MarR; KEGG: afu:AF0363 transcriptional repressor (CinR).
  
     0.612
Ferp_0593
PFAM: Protein of unknown function DUF555; KEGG: afu:AF0282 hypothetical protein; Belongs to the UPF0212 family.
  
     0.599
Ferp_1160
PFAM: protein of unknown function DUF106 transmembrane; KEGG: afu:AF1901 hypothetical protein.
  
     0.593
Your Current Organism:
Ferroglobus placidus
NCBI taxonomy Id: 589924
Other names: F. placidus DSM 10642, Ferroglobus placidus AEDII12DO, Ferroglobus placidus DSM 10642, Ferroglobus placidus str. DSM 10642, Ferroglobus placidus strain DSM 10642
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.