STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ferp_0997PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: rci:LRC441 sulfopyruvate decarboxylase, alpha chain. (360 aa)    
Predicted Functional Partners:
Ferp_0996
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mhu:Mhun_2977 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
 
   
 0.943
Ferp_0998
Protein of unknown function DUF84; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
       0.773
Ferp_0999
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: afu:AF0902 hypothetical protein.
       0.773
Ferp_0853
KEGG: mpl:Mpal_1155 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein.
 
    0.716
Ferp_0737
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
     
 0.684
Ferp_2213
TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: afu:AF0551 threonine synthase.
     
 0.684
mtd
Methylenetetrahydromethanopterin dehydrogenase; Catalyzes the oxidation of methylene-H(4)MPT to methenyl- H(4)MPT(+).
  
   
 0.670
cofC
2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
   
 0.657
mfnB
Protein of unknown function DUF556; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
  
   
 0.656
Ferp_0088
PFAM: transcriptional regulator TrmB; KEGG: neq:NEQ098 hypothetical protein.
  
    0.644
Your Current Organism:
Ferroglobus placidus
NCBI taxonomy Id: 589924
Other names: F. placidus DSM 10642, Ferroglobus placidus AEDII12DO, Ferroglobus placidus DSM 10642, Ferroglobus placidus str. DSM 10642, Ferroglobus placidus strain DSM 10642
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