STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ferp_1586PFAM: DNA methylase N-4/N-6 domain protein; KEGG: tna:CTN_0340 M4C-methyltransferase. (303 aa)    
Predicted Functional Partners:
Ferp_1587
KEGG: hypothetical protein.
       0.773
Ferp_1589
PFAM: protein of unknown function DUF87; SMART: AAA ATPase; KEGG: cyn:Cyan7425_1870 protein of unknown function DUF87.
 
    0.679
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.639
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
    0.636
Ferp_1588
PFAM: RNA-binding S4 domain protein; ribosomal RNA methyltransferase RrmJ/FtsJ; SMART: RNA-binding S4 domain protein; KEGG: afu:AF2184 hypothetical protein.
       0.584
Ferp_1591
PFAM: NurA domain; KEGG: amr:AM1_5312 hypothetical protein.
 
     0.580
Ferp_1592
PFAM: SMC domain protein; KEGG: cyn:Cyan7425_2343 SMC domain protein.
     
 0.579
Ferp_1590
KEGG: cph:Cpha266_1393 hypothetical protein.
       0.558
Ferp_2132
TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: mvu:Metvu_0366 DNA-cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
  
 0.539
Ferp_1593
PFAM: metallophosphoesterase; KEGG: rci:RRC95 DNA repair exonuclease (RAD32/Mre11-like).
  
    0.504
Your Current Organism:
Ferroglobus placidus
NCBI taxonomy Id: 589924
Other names: F. placidus DSM 10642, Ferroglobus placidus AEDII12DO, Ferroglobus placidus DSM 10642, Ferroglobus placidus str. DSM 10642, Ferroglobus placidus strain DSM 10642
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