node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ferp_0598 | Ferp_1994 | Ferp_0598 | Ferp_1994 | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | 0.696 |
Ferp_0598 | Ferp_1997 | Ferp_0598 | Ferp_1997 | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 anthranilate synthase component II. | 0.502 |
Ferp_0598 | Ferp_2251 | Ferp_0598 | Ferp_2251 | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | PFAM: prephenate dehydratase; Chorismate mutase, type II; Prephenate dehydrogenase; amino acid-binding ACT domain protein; KEGG: afu:AF0227 chorismate mutase/prephenate dehydratase (PheA). | 0.908 |
Ferp_0598 | hisG | Ferp_0598 | Ferp_0679 | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.699 |
Ferp_0598 | trpA | Ferp_0598 | Ferp_2000 | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.941 |
Ferp_0598 | trpB | Ferp_0598 | Ferp_1322 | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.902 |
Ferp_0598 | trpB-2 | Ferp_0598 | Ferp_1999 | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.958 |
Ferp_0598 | trpD | Ferp_0598 | Ferp_1995 | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.460 |
Ferp_0598 | trpE | Ferp_0598 | Ferp_1996 | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.489 |
Ferp_0598 | trpF | Ferp_0598 | Ferp_1998 | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: pab:PAB2047 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.670 |
Ferp_1994 | Ferp_0598 | Ferp_1994 | Ferp_0598 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | KEGG: afu:AF2138 phosphoserine phosphatase (SerB); TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; amino acid-binding ACT domain protein. | 0.696 |
Ferp_1994 | Ferp_1997 | Ferp_1994 | Ferp_1997 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: mvn:Mevan_0330 anthranilate synthase component II. | 0.997 |
Ferp_1994 | Ferp_2251 | Ferp_1994 | Ferp_2251 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | PFAM: prephenate dehydratase; Chorismate mutase, type II; Prephenate dehydrogenase; amino acid-binding ACT domain protein; KEGG: afu:AF0227 chorismate mutase/prephenate dehydratase (PheA). | 0.902 |
Ferp_1994 | hisG | Ferp_1994 | Ferp_0679 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.630 |
Ferp_1994 | trpA | Ferp_1994 | Ferp_2000 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.999 |
Ferp_1994 | trpB | Ferp_1994 | Ferp_1322 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.955 |
Ferp_1994 | trpB-2 | Ferp_1994 | Ferp_1999 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
Ferp_1994 | trpD | Ferp_1994 | Ferp_1995 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
Ferp_1994 | trpE | Ferp_1994 | Ferp_1996 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
Ferp_1994 | trpF | Ferp_1994 | Ferp_1998 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: mae:Maeo_1115 indole-3-glycerol-phosphate synthase. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: pab:PAB2047 N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.999 |