Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ferp_2001PFAM: Lactate/malate dehydrogenase; KEGG: afu:AF0855 L-malate dehydrogenase, NAD+-dependent (MdhA); Belongs to the LDH/MDH superfamily. (295 aa)    
Predicted Functional Partners:
Ferp_0810
KEGG: afu:AF1340 citrate synthase (CitZ); TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
  
 0.998
Ferp_0862
KEGG: afu:AF0647 isocitrate dehydrogenase, NADP (icd); TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase.
  
 0.982
Ferp_2030
TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; KEGG: afu:AF1099 fumarate hydratase.
  
 
 0.981
Ferp_2031
KEGG: afu:AF1098 fumarate hydratase; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region.
  
 
 0.977
Ferp_0239
TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: afu:AF1252m oxaloacetate decarboxylase.
    
 0.957
ppcA
Phosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family.
     
 0.944
Ferp_1199
PFAM: aminotransferase class I and II; KEGG: afu:AF2366 aspartate aminotransferase (AspB-1).
  
 0.932
Ferp_2446
PFAM: aminotransferase class I and II; KEGG: afu:AF2129 aspartate aminotransferase.
  
 0.932
Ferp_0744
KEGG: pmx:PERMA_0022 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 0.928
Ferp_1709
KEGG: afu:AF1829 F420H2:quinone oxidoreductase, 39.7 kDa subunit, putative; TIGRFAM: NADH-quinone oxidoreductase, B subunit; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; NADH dehydrogenase (ubiquinone) 30 kDa subunit.
  
 0.925
Your Current Organism:
Ferroglobus placidus
NCBI taxonomy Id: 589924
Other names: F. placidus DSM 10642, Ferroglobus placidus AEDII12DO, Ferroglobus placidus DSM 10642, Ferroglobus placidus str. DSM 10642, Ferroglobus placidus strain DSM 10642
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