Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ferp_2011PFAM: Protein of unknown function UPF0179; KEGG: afu:AF2154 hypothetical protein; Belongs to the UPF0179 family. (146 aa)    
Predicted Functional Partners:
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
 
     0.720
Ferp_0275
PFAM: RNA polymerase Rpb4; KEGG: afu:AF1530 hypothetical protein.
 
     0.710
Ferp_2144
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: afu:AF1787 hypothetical protein.
  
     0.669
Ferp_0786
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: afu:AF1012 hypothetical protein.
  
     0.660
Ferp_0465
KEGG: afu:AF0779 hypothetical protein.
  
     0.642
Ferp_1812
PFAM: PUA domain containing protein; Queuine/other tRNA-ribosyltransferase; SMART: PUA domain containing protein; KEGG: afu:AF0587 hypothetical protein.
  
     0.642
Ferp_0213
PFAM: Protein of unknown function DUF63; KEGG: afu:AF0462 hypothetical protein.
 
   
 0.635
Ferp_1320
KEGG: afu:AF0779 hypothetical protein.
  
     0.631
mptD
Protein of unknown function DUF381; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
  
     0.620
rpl40e
KEGG: afu:AF1430 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
  
     0.612
Your Current Organism:
Ferroglobus placidus
NCBI taxonomy Id: 589924
Other names: F. placidus DSM 10642, Ferroglobus placidus AEDII12DO, Ferroglobus placidus DSM 10642, Ferroglobus placidus str. DSM 10642, Ferroglobus placidus strain DSM 10642
Server load: low (16%) [HD]