STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcAPhosphoenolpyruvate carboxylase; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family. (476 aa)    
Predicted Functional Partners:
Ferp_2001
PFAM: Lactate/malate dehydrogenase; KEGG: afu:AF0855 L-malate dehydrogenase, NAD+-dependent (MdhA); Belongs to the LDH/MDH superfamily.
     
 0.950
Ferp_0322
TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: afu:AF0220 pyruvate carboxylase subunit A.
  
  
 0.928
Ferp_0239
TIGRFAM: oxaloacetate decarboxylase alpha subunit; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: afu:AF1252m oxaloacetate decarboxylase.
     
 0.923
Ferp_0085
PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; KEGG: tpe:Tpen_0588 phosphoenolpyruvate synthase.
     
 0.917
Ferp_2110
TIGRFAM: phosphoenolpyruvate synthase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; KEGG: afu:AF0710 phosphoenolpyruvate synthase.
     
 0.917
Ferp_0744
KEGG: pmx:PERMA_0022 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
     
 0.907
Ferp_0810
KEGG: afu:AF1340 citrate synthase (CitZ); TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
     
 0.901
Ferp_0086
PFAM: PEP-utilising protein mobile region; KEGG: geo:Geob_0142 PEP-utilising protein mobile region.
     
  0.900
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
  0.900
Ferp_1614
KEGG: dhd:Dhaf_3925 hypothetical protein.
  
  
  0.823
Your Current Organism:
Ferroglobus placidus
NCBI taxonomy Id: 589924
Other names: F. placidus DSM 10642, Ferroglobus placidus AEDII12DO, Ferroglobus placidus DSM 10642, Ferroglobus placidus str. DSM 10642, Ferroglobus placidus strain DSM 10642
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