STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3BFD2_CANTCP-loop containing nucleoside triphosphate hydrolase protein. (1038 aa)    
Predicted Functional Partners:
G3B3U1_CANTC
ATP-dependent DNA helicase.
   
 
 0.937
G3B8N9_CANTC
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.922
G3B8Y8_CANTC
DNA repair protein rad10.
    
 0.899
G3B9F7_CANTC
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 
 0.873
G3B6S1_CANTC
Crossover junction endonuclease MUS81.
    
 0.856
G3AXH2_CANTC
Uncharacterized protein.
   
 0.843
G3B207_CANTC
Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.
    
 0.815
G3B788_CANTC
SMC_N domain-containing protein.
   
 
 0.815
G3B709_CANTC
P-loop containing nucleoside triphosphate hydrolase protein.
    
 
 0.813
G3AYS4_CANTC
Polyubiquitin-tagged protein recognition complex, Npl4 component.
    
 0.800
Your Current Organism:
Yamadazyma tenuis
NCBI taxonomy Id: 590646
Other names: Candida tenuis ATCC 10573, Y. tenuis ATCC 10573, Yamadazyma tenuis ATCC 10573
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