STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORB34094.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)    
Predicted Functional Partners:
ORB45850.1
Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
ORB40913.1
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 0.989
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.957
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.949
ORB45153.1
Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.938
ORB39845.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.933
ORB45888.1
Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
  
 
 0.932
ORB35339.1
Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.929
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.924
Your Current Organism:
Mycobacterium paraseoulense
NCBI taxonomy Id: 590652
Other names: DSM 45000, JCM 16952, KCTC 19145, M. paraseoulense, Mycobacterium paraseoulense Lee et al. 2010, Mycobacterium sp. 31118, strain 31118
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