STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Celf_0485PFAM: TAP domain protein; KEGG: TAP domain protein. (519 aa)    
Predicted Functional Partners:
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
  
    0.688
Celf_0483
SMART: AAA ATPase; KEGG: DNA polymerase III, delta prime subunit.
       0.688
Celf_0484
PFAM: bifunctional deaminase-reductase domain protein; KEGG: sen:SACE_6341 deaminase-reductase domain-containing protein.
  
    0.648
Celf_1653
PFAM: 5'-Nucleotidase domain-containing protein; Endonuclease/exonuclease/phosphatase; metallophosphoesterase; KEGG: 5'-nucleotidase domain protein.
   
  
 0.593
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.529
Celf_2161
KEGG: hypothetical protein.
  
     0.467
Celf_0486
KEGG: hoh:Hoch_2831 hypothetical protein.
       0.445
Celf_0487
Hypothetical protein; KEGG: cak:Caul_2460 response regulator receiver protein.
       0.445
Celf_0481
PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: oxidoreductase domain protein.
  
    0.428
nucS
Protein of unknown function DUF91; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
  
     0.416
Your Current Organism:
Cellulomonas fimi
NCBI taxonomy Id: 590998
Other names: C. fimi ATCC 484, Cellulomonas fimi ATCC 484, Cellulomonas fimi DSM 20113, Cellulomonas fimi str. ATCC 484, Cellulomonas fimi strain ATCC 484
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