STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Celf_0800KEGG: svi:Svir_34920 DNA ligase D/DNA polymerase LigD; TIGRFAM: DNA polymerase LigD, ligase domain protein; DNA ligase D, 3'-phosphoesterase domain protein; PFAM: ATP dependent DNA ligase; ATP dependent DNA ligase domain protein. (491 aa)    
Predicted Functional Partners:
Celf_1917
KEGG: xce:Xcel_2233 DNA polymerase LigD, polymerase domain protein; TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit.
  
 0.998
Celf_1185
PFAM: DNA primase small subunit; KEGG: DNA ligase D, 3'-phosphoesterase domain protein.
  
 0.997
Celf_0509
KEGG: DNA polymerase LigD, polymerase domain protein; TIGRFAM: DNA polymerase LigD, polymerase domain protein; PFAM: DNA primase small subunit.
   
 0.978
Celf_3528
KEGG: exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.
 
 
 0.940
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.877
Celf_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.831
Celf_0419
Regulatory protein MerR; KEGG: transcriptional regulator, MerR family; PFAM: regulatory protein MerR; DNA polymerase III beta chain; SMART: regulatory protein MerR.
   
 0.831
Celf_1919
KEGG: PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein.
 
 0.780
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.756
Celf_1390
KEGG: putative viral-like DNA topoisomerase.
 
 
 
 0.630
Your Current Organism:
Cellulomonas fimi
NCBI taxonomy Id: 590998
Other names: C. fimi ATCC 484, Cellulomonas fimi ATCC 484, Cellulomonas fimi DSM 20113, Cellulomonas fimi str. ATCC 484, Cellulomonas fimi strain ATCC 484
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