node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Celf_0300 | Celf_0968 | Celf_0300 | Celf_0968 | PFAM: aminotransferase class V; KEGG: nca:Noca_3274 alanine-glyoxylate aminotransferase. | PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL4450 putative monomeric sarcosine oxidase (MSOX). | 0.923 |
Celf_0300 | Celf_1195 | Celf_0300 | Celf_1195 | PFAM: aminotransferase class V; KEGG: nca:Noca_3274 alanine-glyoxylate aminotransferase. | PFAM: FAD dependent oxidoreductase; KEGG: glycine/D-amino acid oxidase, deaminating. | 0.923 |
Celf_0300 | Celf_1923 | Celf_0300 | Celf_1923 | PFAM: aminotransferase class V; KEGG: nca:Noca_3274 alanine-glyoxylate aminotransferase. | Threonine aldolase; Manually curated; KEGG: ach:Achl_1651 threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.924 |
Celf_0300 | gcvP | Celf_0300 | Celf_3728 | PFAM: aminotransferase class V; KEGG: nca:Noca_3274 alanine-glyoxylate aminotransferase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.945 |
Celf_0300 | gcvT | Celf_0300 | Celf_3727 | PFAM: aminotransferase class V; KEGG: nca:Noca_3274 alanine-glyoxylate aminotransferase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.938 |
Celf_0300 | glyA | Celf_0300 | Celf_1135 | PFAM: aminotransferase class V; KEGG: nca:Noca_3274 alanine-glyoxylate aminotransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.937 |
Celf_0968 | Celf_0300 | Celf_0968 | Celf_0300 | PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL4450 putative monomeric sarcosine oxidase (MSOX). | PFAM: aminotransferase class V; KEGG: nca:Noca_3274 alanine-glyoxylate aminotransferase. | 0.923 |
Celf_0968 | Celf_1195 | Celf_0968 | Celf_1195 | PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL4450 putative monomeric sarcosine oxidase (MSOX). | PFAM: FAD dependent oxidoreductase; KEGG: glycine/D-amino acid oxidase, deaminating. | 0.928 |
Celf_0968 | Celf_1657 | Celf_0968 | Celf_1657 | PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL4450 putative monomeric sarcosine oxidase (MSOX). | KEGG: phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; TENA/THI-4 domain-containing protein. | 0.588 |
Celf_0968 | Celf_1923 | Celf_0968 | Celf_1923 | PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL4450 putative monomeric sarcosine oxidase (MSOX). | Threonine aldolase; Manually curated; KEGG: ach:Achl_1651 threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.903 |
Celf_0968 | Celf_2285 | Celf_0968 | Celf_2285 | PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL4450 putative monomeric sarcosine oxidase (MSOX). | KEGG: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; Carbamoyl-phosphate synthetase large chain oligomerisation; Rhodanese domain protein; SMART: Rhodanese domain protein. | 0.845 |
Celf_0968 | gcvP | Celf_0968 | Celf_3728 | PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL4450 putative monomeric sarcosine oxidase (MSOX). | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.917 |
Celf_0968 | gcvT | Celf_0968 | Celf_3727 | PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL4450 putative monomeric sarcosine oxidase (MSOX). | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.680 |
Celf_0968 | glyA | Celf_0968 | Celf_1135 | PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL4450 putative monomeric sarcosine oxidase (MSOX). | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.912 |
Celf_1194 | Celf_1195 | Celf_1194 | Celf_1195 | KEGG: amino acid-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3. | PFAM: FAD dependent oxidoreductase; KEGG: glycine/D-amino acid oxidase, deaminating. | 0.681 |
Celf_1194 | Celf_1196 | Celf_1194 | Celf_1196 | KEGG: amino acid-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3. | Luciferase family oxidoreductase, group 1; KEGG: flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; TIGRFAM: luciferase family oxidoreductase, group 1; PFAM: Luciferase-like, subgroup. | 0.537 |
Celf_1195 | Celf_0300 | Celf_1195 | Celf_0300 | PFAM: FAD dependent oxidoreductase; KEGG: glycine/D-amino acid oxidase, deaminating. | PFAM: aminotransferase class V; KEGG: nca:Noca_3274 alanine-glyoxylate aminotransferase. | 0.923 |
Celf_1195 | Celf_0968 | Celf_1195 | Celf_0968 | PFAM: FAD dependent oxidoreductase; KEGG: glycine/D-amino acid oxidase, deaminating. | PFAM: FAD dependent oxidoreductase; KEGG: fal:FRAAL4450 putative monomeric sarcosine oxidase (MSOX). | 0.928 |
Celf_1195 | Celf_1194 | Celf_1195 | Celf_1194 | PFAM: FAD dependent oxidoreductase; KEGG: glycine/D-amino acid oxidase, deaminating. | KEGG: amino acid-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3. | 0.681 |
Celf_1195 | Celf_1196 | Celf_1195 | Celf_1196 | PFAM: FAD dependent oxidoreductase; KEGG: glycine/D-amino acid oxidase, deaminating. | Luciferase family oxidoreductase, group 1; KEGG: flavin-dependent oxidoreductase, F420-dependent methylene-tetrahydromethanopterin reductase; TIGRFAM: luciferase family oxidoreductase, group 1; PFAM: Luciferase-like, subgroup. | 0.601 |